Pub. date: 2008 | Online Pub. Date: April 21, 2008 | DOI: 10.4135/9781412963855 | Print ISBN: 9781412941860 | Online ISBN: 9781412963855 | Publisher:SAGE Publications, Inc.About this encyclopedia
Crossover studies, sometimes referred to as case-crossover studies, are a type of clinical trial design where a participant experiences both the intervention and control aspects of the study. Participants are first randomized into either the intervention or control arms of a study for a previously determined amount of time and observed. After that time has concluded, these participants essentially “cross over” into another arm of the study, thus serving as their own controls in the study. This type of study is appealing because of its efficiency and precision. Crossover studies are efficient because participants are ...