Pub. date: 2008 | Online Pub. Date: April 21, 2008 | DOI: 10.4135/9781412963855 | Print ISBN: 9781412941860 | Online ISBN: 9781412963855| Publisher:SAGE Publications, Inc.About this encyclopedia
Bimal P. Chaudhari
Also known as somatic mutation, acquired mutation is an alteration of genetic matter that occurs after the time of conception and affects somatic cells (as opposed to mutations that affect germ cells). A principal consequence of affecting only somatic cells is that such mutations cannot be passed to offspring. However, acquired mutations are normally transmitted to all cells descended from the original mutant cell, giving rise of a clone (colony) of cells bearing the acquired mutation. Mutations of this ...