Pub. date: 2008 | Online Pub. Date: May 22, 2008 | DOI: 10.4135/9781848605985 | Print ISBN: 9781847870483 | Online ISBN: 9781848605985| Publisher:SAGE Publications LtdAbout this handbook
Chapter 20: The Role of Pharmacogenomics in Personalized Medicine
The role of pharmacogenomics in personalized medicine In the 21st century, personalized medicine is a growing trend. The pharmaceutical industry is very gradually moving away from the blockbuster model of drug development, which is based on the theory that “one drug treats most patients most of the time,” to a model whereby medicines are designed to treat the specific patient, not the population as a whole. Pharmaceutical companies that are able to navigate the path from the blockbuster to the personalized medicine model of drug development will become early leaders in this new era of medicine. Several new technologies will facilitate the development of personalized medicine; key among them is pharmacogenomics, which determines how genomic variations in people modify the behavior of drugs. Pharmacogenomics combines pharmacology with genomic information and can be used during the development of new drugs to identify the most appropriate drug to treat an individual based ...