Pub. date: 2008 | Online Pub. Date: April 21, 2008 | DOI: 10.4135/9781412963855 | Print ISBN: 9781412941860 | Online ISBN: 9781412963855| Publisher:SAGE Publications, Inc.About this encyclopedia
Electrophysiology is a study of the electrical properties that exist within biological cells and tissues, and this has developed to include the ability of these cells to react to electrical current. To do this, researchers have had to measure the change of voltage and also the flow of electric current covering a variety of scales, ranging from places such as the heart to single-ion channel proteins. The origin of electrophysiology goes back to the research of the German, Emil Heinrich Du Bois-Rey-mond, from Berlin who, during his work at the University of Berlin, decided to concentrate on electrical activity in nerve and muscle fibers. His initial work was on fish and that they were capable of generating electrical currents on their own. From this, he turned to researching electrical conduction along muscle and nerve fibers which led ...