Pub. date: 2008 | Online Pub. Date: September 15, 2008 | DOI: 10.4135/9781412963954 | Print ISBN: 9781412959087 | Online ISBN: 9781412963954| Publisher:SAGE Publications, Inc.About this encyclopedia
EXPERIMENTAL MODELS HELP researchers understand the developmental and function of a biological process. A model system in biological research refers to anything that scientists use to recreate aspects of a disease or any biological process. The study of a biological process has made intensive use of experimental models, as performing such work in human is difficult for experimental, practical, and ethical reasons. A model can be a cell living in a dish. Or it can be used the animal models that have long played an important role in biology are both invertebrates (e.g., Drosophila, Aplysia) and vertebrates (e.g., Zebrafish, rodents, non—human primates), as well as mutant and transgenic animals that have revolutionized scientists' ability to characterize normal, abnormal, and restorative development. Stem cells can be clinically beneficial through a range of mechanism—encapsulated in the idea of therapeutic plasticity. The field of stem cell biology and regenerative medicine is rapidly moving ...